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Tramadol Drug Interactions

tramadol-100mg-boxIf you want to take Tramadol you want to be sure you are not taking any other medications that are going to interact with it badly. Certain medications you might be taking or even some over the counter items can cause potential problems. Use this guide to help you, but only use these as a starting point. Let a doctor look into your specific situation.

What are other drugs that might negatively interact with Tramadol?

If you are taking Tramadol then you will want to speak with a doctor first so they can discuss specific medications you are using that will increase your chances of problems such as seizures. One of these medications would be an MAO inhibitor. These might be drugs like isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam).

If you use antidepressants medications then these might also interact badly with Tramadol. There are several of these medications, but here is a list of just a few types of antidepressants you need to look out for when taking Tramadol; amitriptyline (Elavil, Vanatrip), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), or sertraline (Zoloft)

If you are taking any type of cold medicine or allergy medicine, you need to tell a doctor. These types of medications contain active ingredients that may interact badly with Tramadol. It does not stop there. You need to tell your doctor if you are taking any kind of sleeping pills, muscle relaxers, and any type of medication designed to help you deal with anxiety.

These types of medications are going to increase your chances of a sleeping problem when taking Tramadol and drowsiness. The drug already causes these side effects as they are the most common. Sleeping pills and medications for seizures and anxiety are only going to increase the effect of these symptoms.

Medications for Attention Deficit Disorder (ADHD) such as Adderall, Ritalin, and Strattera also may interact badly with Tramadol. So you need to be aware of this. Also various antibiotics can cause negative drug interactions. Here are a few; clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), linezolid (Zyvox), rifampin (Rifadin, Rimactane, Rifater); or telithromycin (Ketek).

If you are taking anti-fungal medications these might have a bad reaction to Tramadol. Cancer medications can definitely cause problems. If you are taking any medication for a heart rhythm that is going to be a potential problem. Any type of heart or blood pressure medications need to be discussed with a doctor, as well as medications for HIV/AIDS. Migraine headache medication may also effect Tramadol effectiveness.

All of these different types of medications can cause problems with Tramadol. Obviously everyone is not going to be impacted the same way. This is why it is so important to discuss taking this medication with a doctor, even if you might not get it prescribed to you by them. Adjustments can be made in order to allow you to keep taking other medications you need, and at the same time not put your health at risk while taking Tramadol.

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One comment

  1. Hello. I have been taking tramadol for a month for severe spinal stenosis, slipped vertebra, degenerated disc, etc….I refuse to go back to my pain management clinic as they are rude and unprofessional. I have an appt ties and in no way shape or form will I step foot in his office. However my pain is so acute. I have an appointment with a neurosurgeon July 20. My occupation requires me to be on my feet on day. Brutal and not sure how I will make it until july 20. Also I signed a contract with that unprofessional pain med clinic.
    Please advise. Thank you!

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