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Prozac vs. Zoloft

Prozac and Zoloft are effective prescription drugs aimed at the treatment of depression, anxiety, and a range of other psychological disorders. Both drugs are classified as selective serotonin reuptake inhibitors, which balance the levels of serotonin in the brain. Generally, the remedies are used to eliminate the signs of depression and improve mood. Apart from the main effects, they also trigger appetite, increase energy levels, and promote better sleep. Zoloft and Prozac are also widely used to reduce the signs of fear, anxiety, panic attacks, and compulsive behaviors.

Basically, the drugs are ultimately similar as they belong to the same group of remedies and produce a similar influence on the organism. However, there are slight differences in certain features and characteristics of depression medications.

Key Features of Prozac and Zoloft

Despite both remedies can be used for successful treatment of major depression, panic disorders, and obsessive-compulsive issues, only Zoloft can help with such issues as social phobia, post-traumatic stress disorder, and premenstrual dysphoric disorder, while only Prozac may be effective for the improvement of bulimia nervosa.

Besides, both medications can sometimes be used off-label for the treatment of other conditions that are not listed in the safety guide. Some of them may include some sleeping and eating problems.

Another significant difference between these SSRI drugs is the safety of use. Prozac is approved for the treatment of depression only in patients over 8 years old, while Zoloft can be taken from 6 years old.

Both remedies are available in the capsule form, though Zoloft is also offered as an oral liquid concentrate solution. The doses of Zoloft and Prozac may also differ, but anyway, they should be individually prescribed to each patient.

Zoloft and Prozac: Interaction with Other Treatments

Regarding warnings and restrictions for use, as well as possible interactions, SSRI drugs are very similar. Both of them may interact with other prescription or non-prescription treatments, causing significant health problems. Contact your medical specialist before you start the treatment course. Inform your medical specialist about the use of:

  • Linezolid;
  • Pirozide;
  • Monoamine oxidase inhibitors;
  • Methylene blue injections, and other remedies.

Zoloft and Prozac are not recommended for pregnant and breastfeeding women as their components can produce a negative impact on the health of both a mother and a child.

Possible Side Effects

Start with the lowest dose of Zoloft or Prozac to eliminate the risk of any adverse reactions. These depression treatments are likely to cause the same side effects. The most common of them are:

  • Diarrhea;
  • Dizziness;
  • Nausea, or vomiting;
  • Sex-related problems;
  • Abnormal nervousness and anxiety;
  • Unusual changes in weight;
  • Dry mouth, etc.

Additionally, antidepressants may trigger more serious health problems. Zoloft and Prozac increase the risk of suicidal thoughts and actions in children and young adults.

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