Isoniazid, also known as nydrazid, is one of the oldest antidepressants in use. The medication’s main use is to treat tuberculosis. However, it was found that it is also useful in treating depression. The medicine works best when it is used with a combination of other drugs.
How it works
The drug is antibacterial and therefore works by stopping the growth of bacteria. When treating depression, the medication works as a mood elevator by affecting the chemicals in the brain that are responsible for generating various moods. These include neurotransmitters such as serotonin and dopamine.
The main purpose of this medication is to treat tuberculosis. Since it is antibacterial, the medication will not be useful in treating viral infections such as the common cold or the flu. The drug is useful in treating depression as well. Using the drug for unrelated health issues can affect its effectiveness to a great extent.
This medication is usually consumed o an empty stomach – ideally 1 or 2 hours before/after your meal. The dosage will be determined according to your age, weight, response to the treatment and medical condition. The medication is most effective when the dosage of the drug is maintained at the same level on a constant basis. Thus, it is important to ensure that you take the medication daily at the same time and same amount. Setting an alarm can be helpful in this case. You must continue to use this medication throughout the prescribed period – even if your symptoms disappear. Skipping a dose may result in the condition worsening. So, remember to stick to your schedule.
Listed below are some effects that you may/may not experience during this treatment period.
Changes in vision
Swelling of face
Yellowing of skin/eyes
Loss of appetite
If you do experience any of the above symptoms, make sure to contact your healthcare provider immediately.
Following the guidelines mentioned below will enable you to decrease the risk of being affected by the medication’s side effects.
You must not consume alcohol during your treatment period since it can result in liver damage and nerve problems.
The medication can affect your blood sugar level. So, take regular tests to stay informed about your health condition.
Anyone above the age of 35 must be careful with the dosage since they are more susceptible to the side effects of the medication.
Stop taking the medication temporarily during periods of pregnancy and breastfeeding since it can affect the health of the baby.
This medication can result negatively to a lot of food items. Thus, you must plan your diet with your healthcare provider to reduce the risk of allergic reactions. For instance, avoid consuming red wine, cheese and seafood since they can affect negatively to any type of tricyclic antidepressant. Consuming such items can increase your blood pressure, heartbeat and result in flushing of skin and dizziness.
In order to reduce certain side effects such as nerve problems, your physician might ask you to take vitamin B6. Taking this vitamin can be quite helpful – especially if you have a history of poor nutrition, alcohol abuse or diabetes.